Molecularly imprinted polymers (MIPs) are synthetic materials made with synthetic recognition sites that can specifically bind a target compound preferentially to other closely related compounds. These materials are obtained by polymerization of functional monomers (which are selected based on their ability to interact with the functional groups of the template molecule) and cross-linking around a template molecule, resulting in a highly cross-linked three-dimensional polymer network. Once polymerization is complete, the template molecule is extracted, leaving binding sites with shape, size, and functionalities within the polymer network complementary to the target compound.
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